Cagrilintide 10mg

Cagrilintide 10 mg — Research Peptide

Cagrilintide is a long-acting acylated amylin analogue developed by Novo Nordisk, acting as a nonselective agonist at the amylin receptors (AMY1/2/3) and the calcitonin receptor (CTR). In the phase 3 REDEFINE 1 trial, the combination of cagrilintide and semaglutide (studied as “CagriSema”) led to at least 20% weight loss in 60% of participants.

Product Details

• Net weight: 10 mg (lyophilised)
• Purity: ≥98.9% (HPLC-verified)
• Identity confirmed by LC-MS
• Batch-specific COA included

Receptor Target

• Amylin receptors (AMY1/2/3) and calcitonin receptor (CTR) — nonselective agonist
• Enhances satiety and slows gastric emptying via brainstem (area postrema) signalling
• Synergistic mechanism when studied alongside GLP-1 receptor agonists such as semaglutide

For research purposes only. Not intended for human use.

Reconstitution: Example Calculation

For a working concentration of 10 mg/ml, reconstitute the 10 mg vial with 1 ml of sterile bacteriostatic water (BAC water). Inject the water slowly along the inside wall of the vial and swirl gently rather than shaking.

Frequently Asked Questions

How does cagrilintide differ from GLP-1 receptor agonists like semaglutide?
Cagrilintide acts through amylin and calcitonin receptors rather than the GLP-1 receptor. Research literature describes the combination of both mechanisms as synergistic — semaglutide slows gastric emptying and suppresses appetite, while cagrilintide further enhances satiety via brainstem signalling pathways.

Is cagrilintide often studied in combination with other peptides?
Yes — current research literature predominantly studies cagrilintide together with semaglutide (a GLP-1 receptor agonist) to capture additive or synergistic effects on satiety and metabolism.

Quality Assurance

Every production batch goes through independent dual verification: HPLC analysis to determine purity, and LC-MS analysis to unambiguously confirm molecular mass and correct peptide sequence. Only after passing both checks is a batch released, shipped with a batch-specific Certificate of Analysis (COA).