Ipamorelin 10mg – Selective Growth Hormone Secretagogue
Ipamorelin is a synthetic pentapeptide developed by Novo Nordisk and, since its initial description (Raun et al., 1998), has been considered the most selective growth hormone secretagogue (GHS) among the ghrelin mimetics. Unlike GHRP-2 or GHRP-6, it does not increase cortisol or prolactin.
This 10mg vial is suitable for research approaches related to pulsatile GH release and selective receptor pharmacology.
Mechanism of action
Ipamorelin binds selectively to the ghrelin receptor (GHSR-1a) in the pituitary gland, thereby stimulating the pulsatile release of growth hormone (GH), which secondarily leads to increased IGF-1 production in the liver. Other pituitary hormones (prolactin, ACTH, FSH, LH) are not significantly affected—a crucial distinguishing feature compared to non-selective GH secretagogues.
Technical specifications
| Characteristic | Details |
|---|---|
| Product name | Ipamorelin (NNC 26-0161) |
| CAS number | 170851-70-4 |
| Crowd | 10mg |
| form | Lyophilized powder |
| molecular formula | C₃₈H₄₉N₉O₅ |
| Molecular weight | 711.86 g/mol |
| purity | ≥98.9 % (HPLC) |
| analysis | HPLC / LC-MS |
| storage | 2–8 °C |
Storage: Store at −20 °C (long-term); after reconstitution at 4 °C, use within 2–4 weeks. Protect from light and moisture.
Source: Raun K et al., „Ipamorelin, the first selective growth hormone secretagogue,“ European Journal of Endocrinology, 1998
Disclaimer: Not intended for human or veterinary use. For laboratory research purposes only. Not for diagnostic or therapeutic purposes.
Reconstitution: Example calculation
For a working concentration of 10 mg/ml, the 10 mg vial is reconstituted with 1 ml of sterile bacteriostatic water (BAC water). Slowly inject the water along the inside of the vial and gently swirl it instead of shaking.
Frequently Asked Questions
What distinguishes ipamorelin from other ghrelin mimetics?
In contrast to GHRP-2 or GHRP-6, Ipamorelin does not increase cortisol or prolactin levels, according to Raun et al. (1998), making it a more selective research tool.
Is Ipamorelin frequently studied in combination with other peptides?
In research literature, Ipamorelin is often studied in combination with GHRH analogues such as CJC-1295 to capture synergistic effects on GH secretion.
Quality assurance
Each production batch undergoes independent dual testing: HPLC analysis to determine purity and LC-MS analysis to definitively verify molecular mass and correct peptide sequence. Only after passing this test is a batch released.
Reviews
There are no reviews yet.